Eventually, the player has a boss battle against Tom Morello from Rise Against the Machine, Slash from Guns n’ Roses etc. By beating 3 songs and 1 encore on each level, the player proceeds to the next. In order to unlock each arena, the player has to go through career mode.
The environment that the game is based in differs from level to level. The player, in story mode, will play the lead guitar, while in practice the player has the option to choose whether they can play rhythm or bass as well. Guitar Hero III: Legends of Rock does not change much in terms of gameplay in comparison to its predecessors and it retains the basic idea of scrolling notes in sync with the screen.